|
|
acetoacetyl-CoA + H2O + acetyl-CoA <=> H+ + CoA + (S)-3-hydroxy-3-methylglutaryl-CoA
|
2.3.3.10
hydroxymethylglutaryl-CoA synthase
|
–
|
| |
BRENDA:
BR44119
KEGG:
R01978
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
SABIO-RK:
2021
|
|
|
|
(R)-3-hydroxybutanoate + NAD+ <=> acetoacetate + NADH + H+
|
1.1.1.30
3-hydroxybutyrate dehydrogenase
|
–
|
| |
BRENDA:
BR29293
KEGG:
R01361
MetaCyc:
3-HYDROXYBUTYRATE-DEHYDROGENASE-RXN
SABIO-RK:
1565
|
|
|
|
acetyl-CoA <=> acetoacetyl-CoA + CoA
|
1.1.1.34
hydroxymethylglutaryl-CoA reductase (NADPH)
2.3.1.155
acetyl-CoA C-myristoyltransferase
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.38
[acyl-carrier-protein] S-acetyltransferase
2.3.1.9
acetyl-CoA C-acetyltransferase
|
–
–
–
–
–
|
| |
BRENDA:
BR44092
KEGG:
R00238
MetaCyc:
ACETYL-COA-ACETYLTRANSFER-RXN
SABIO-RK:
531
|
|
|
|
(S)-3-hydroxy-3-methylglutaryl-CoA <=> acetoacetate + acetyl-CoA
|
4.1.3.4
hydroxymethylglutaryl-CoA lyase
|
–
|
| |
BRENDA:
BR395;
BS416230
KEGG:
R01360
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN
SABIO-RK:
1564
|
|
|
|
acetoacetate + H+ <=> acetone + CO2
|
1.8.1.5
2-oxopropyl-CoM reductase (carboxylating)
4.1.1.4
acetoacetate decarboxylase
|
–
–
|
| |
BRENDA:
BR299
KEGG:
R01366
MetaCyc:
ACETOACETATE-DECARBOXYLASE-RXN
SABIO-RK:
1568
|
|
|
|
succinyl-CoA + acetoacetate <=> succinate + acetoacetyl-CoA
|
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.5
3-oxoacid CoA-transferase
|
–
–
|
| |
BRENDA:
BS360598
KEGG:
R00410
MetaCyc:
RXNI-2
SABIO-RK:
867
|
|
